OXIDATIVE CELLULAR DAMAGE AND THE REDUCTION OF APE/REF-1 EXPRESSION AFTER EXPERIMENTAL TRAUMATIC BRAIN INJURY

Oxidative Cellular Damage and the Reduction of APE/Ref-1 Expression after Experimental Traumatic Brain Injury

The Janitorial DNA repair enzyme, apurinic/apyrimidinic endonuclease (or redox effector factor-1, APE/Ref-1), is involved in base excision repair of apurinic/apyrimidinic sites after oxidative DNA damage.We investigated the expression of APE/Ref-1 and its relationship to oxidative stress after severe traumatic brain injury produced by controlled co

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Unleashing the Full Potential of Oncolytic Adenoviruses against Cancer by Applying RNA Interference: The Force Awakens

Oncolytic virus therapy of cancer is an actively pursued field of research.Viruses that were once considered as pathogens threatening the wellbeing of humans and animals alike are with every passing decade more prominently regarded as vehicles for genetic and oncolytic therapies.Oncolytic viruses kill cancer cells, sparing healthy tissues, and prov

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DETERMINATION OF THE NATURE OF ENCROACHMENT ON BLOOD DONATION

The relevance of the work is due to the fact that in June 2022, changes were made to the law on blood donation regarding the transfer of blood and its components for the production of medicines and medical devices.As a result of innovations, blood and its components have become the subject of Q Posket contractual relations between blood centers and

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